MTS Derma Roller aka Micro Needling Coming Soon!!   Micro Needling Procedure..............................................................................$445 1 Hour Procedure:  First Procedure of Series Microdermabrasion or Facial Steam with Enzyme  (Based on skin type) Application of Light Numbing Product Light Massage with Performance Serum  (Based on skin Treatment) Re- application of Performance Serum Final application of Sunblock Moisturizer (Included: Home use skin products:: 1- A-Stem Cell Serum & 1- A-Stem Cell Eye Serum at the First Procedure Series) *** Second through Tenth Procedure $350 each Treatment *****Purchased in Series of 10 receive 10% discount  ($324 savings) Micro Needling- At the heart of Microneedle Therapy System (MTS) is the patented MTS Roller™ – a unique ‘Type I’ FDA-approved supplemental medical tool that is ideal for non-surgical and non-ablative treatment of various skin conditions such as aging (wrinkles, stretching), scarring (acne, surgical), and hyperpigmentation. Clinical studies have shown MTS (microneedle therapy system) to be more effective than ablative treatments like laser resurfacing, dermabrasion, and chemical peel and just as effective as non-ablative treatments like IPL, CO2 laser, and Fraxel in stimulating collagen and elastin production to thicken the skin thereby erasing wrinkles and smoothing scars. Absolute Absorbency MTS Roller™ uses 200 very fine needles to injures the skin sufficiently enough to stimulate collagen/elastin production. Resulting micro-channels also aid in infusing therapeutic serums for greater penetration and increasing overall efficacy. Clinical studies from Europe, U.S. and South Korea have proven that serum absorption is increased by as much as 1,000 times when applied with MTS Roller(1). Clinical studies have also shown that treatment with MTS Roller is more consistent in increasing the thickness of the skin than IPL and other resurfacing treatments(2). There are THREE major advantages having Micro Needling Procedure series: Micro Needling  does the same job that lasers and other ablative methods by increasing the production of collagen with minimal damage to the protective layer of the skin.   Micro Needling  idisis very            is seeeiis effective.  In fact, just as effective as lasers, IPL, Thermage and other ‘machine-based’ treatments, but at a fraction of the cost to practitioners and patients.   Micro Needling  is safe. “Non-surgical and non-ablative” means more ‘forgiving’ and skin-friendly treatments. Patients experience little or no pain, downtime, and risk for complications.   Fast Recuperative Power The gentle stimulus provided by the Micro Needling/  MTS Roller- is far more “skin friendly” and thus far more effective than many other more invasive and more expensive skin treatments. MTS Roller leaves the entire epidermal barrier fully intact; micro-channels created by 200 precision surgical steel needles seal within hours after application: long enough for new collagen-structures to form within the lower layers of the skin and short enough to allow the patient to resume normal schedules quickly. MTS Rollers eliminate all common negative side effects and risks associated with chemical peeling, dermabrasion, and laser-resurfacing. The skin is thicker and ready sooner for additional treatment. Personal MTS models (CR2, CR3) are virtually painless; clinical models (CR5, CR10, CR20) should be used with a topical anesthetic. SKIN FRIENDLY, FASTER RECUPERATION, COST-EFFECTIVE Ablative treatments like dermabrasion, chemical peel and laser re-surfacing to do one thing: remove the protective epidermis to force the body to produce a new tissue layer. However, once the epidermis is removed the lower levels of skin is completely exposed – vulnerable to environmental contamination from dirt, dust, and bacteria. Certain risks must be accepted with these procedures: pain, long-term discomfort, long prevailing inflammation and redness, long healing period, extreme light-sensitivity for a month or more, possible irreversible pigment changes and even additional scarring. Ablative treatments have their limits. Due to different skin structures on neck for instance, laser re-surfacing may not be possible. Moreover, because these treatments leave the skin thinner, in some cases these procedures may actually age the skin. MTS Roller is far more ‘skin friendly’ by doing far less damage and thereby encouraging faster, longer-lasting positive effects. Since the skin can recuperate faster after MTS treatment – often hours after treatment – the patient may see noticeable positive results sooner.  Clinical Features of Micro Needling/ MTS Roller™ MTS Roller is cost-effective compared to conventional treatments – in some cases, less than 10% the cost of other treatments like laser resurfacing.   MTS Roller lasts longer than other rollers – our patented design and superior materials gives MTS Roller twice the lifespan of most other roller brands – up to 6 months if you follow our simple cleaning and care instructions3.   MTS Roller is the highest quality roller on the market today – only MTS Roller is made from surgical quality Lexan (compare with other rollers made from ABS plastic or resin), and the highest quality surgical steel available in the world(3).   MTS Roller is a safer product than other rollers – manufactured under strict ISO9001 standards in our own high-tech clean room facility.   MTS Roller is versatile treatment alternative – applied to a wide range of skin conditions including depressed acne scarring, surgical scars, sun-damaged skin, uneven skin texture, uneven skin coloration (pigmentation), wrinkles and “smile” lines, stretch marks, and cellulite.   Key Points There are no known negative side-effects Extremely high absorption of any type of chemical substance Collagen induction through controlled mechanical stimulation of the dermis It can be used on thin skin It can be used on face, neck and body Realignment of old collagen bundles Complete preservation of the epidermis during the procedure No permanent damage to the skin, no pain during procedure No bleeding, infection, discoloration or other complications on the treated area Enhances Iontophoresis and Sonophoresis treatments Can be used to boost the effects after a Medical Collagen Induction Therapy This type of needling can be done on people who have had laser resurfacing Can be used on areas of the skin where laser resurfacing can not reach Only 24-48 hours healing period completed next day and patient can go into public Only 3-5 days protection from ultraviolet light. Sources: Clinical Study: MTS (Microneedle Therapy System), 5-Month Study; Dr KB Joon, Department of Dermatology, Dongguk University, S. Korea (2006)   Collagen Induction Therapy Comparison (IPL vs Micro-Needling); Drs HS Moon, SE Kim, DS Ko, AY Lee, Dep. of Dermatology, Eulji University School of Medicine and Dongguk University, S. Korea (2006)   Product Comparison Study (MTS Roller vs Dermaroller); manufacturer’s shelf-life and usage study, including known references on materials and usage.

Less Invasive, Less Expensive, More Effective With so many choices, how do you choose from one non-surgical skin treatment over the other? How do you know which is best for you? Here’s an easy comparison of three non-surgical, minimally invasive techniques taking into consideration known side effects, downtime, expected results, and cost. What Happens? All treatments have a common goal: injure the skin just enough to begin natural healing processes. Ablative treatments like chemical peel, dermabrasion, and laser skin resurfacing accomplish this task by removing the entire top layer of skin. Microdermabrasion is also ablative, but it is superficial and cannot treat for deeper imperfections. New technologies like CO2 lasers, Fraxel, Thermage and IPL are non-ablative (they do not remove the top layer) and have demonstrated effectiveness, but the equipment is very expensive thus treatments are very costly to the patient. MTS Roller is unique because it produces similar results without expensive equipment and without removing skin layers; treatments are comparatively inexpensive and pose minimal risks. Treatment Survey   Dermabrasion and Chemical Peels Dermabrasion and Chemical Peels are popular ablative techniques. Dermabrasion requires the clinician to use a power driven hand-held machine with a rotating metal wheel and a diamond fraise or a wire brush to remove the top layers of the skin. It can be performed using a general or a local anesthetic, depending on the area submitted to the treatment. Chemical peels use a mild acid solution to achieve the same effect. To ensure successful outcomes, both ablatives require a great deal of clinical artistry, skill, and experience.   Laser skin resurfacing Laser skin resurfacing uses high intensity light emissions to vaporize the top layers of the skin in order to either remove scars or wrinkles. Like dermabrasion and chemical peel, laser resurfacing stimulates collagen and elastin production in the skin as a means of making wrinkles and other imperfections less visible. Also, like other ablatives, laser resurfacing require a great deal of clinical artistry, skill, and experience to ensure a positive outcome.   Non-Ablative Machine-based treatments Non-Ablative Machine-based treatments include a wide array of recent innovations, many of them quite new and very expensive. Thermage (radio frequency, RF) treatments deliver high energy influences to a large area of tissue with no epidermal injury. The underlying effect is the same as microwave cooking. IPL (intense pulse light) or ‘photorejuvenation’ focuses broad spectrum light onto the skin to influence texture and pigmentation.   Microdermabrasion Microdermabrasion is a milder peeling procedure (ablative); a gentle mechanical peel that uses a stream of crystals (or a diamond tip wand) and suction to gently exfoliate the skin. Home care microderabrasion kits are readily available from many pharmacies and department stores.   MTS Roller™ MTS Roller™ is a mesotherapeutic ‘non-ablative’ non-surgical tool that facilitates a procedure that preserves the top layer of skin while inducing the body to produce collagen and elastin. Treatment involves a roller with needles that ranged from shot length (0.2mm) to long length (2.0mm). The clinical version must be administered by a clinician with a mild topical anesthetic. Personal care versions are available from skin care professionals only. Downtime The downtime required of various skin therapies depends on the depth of the injury caused to the skin. Microdermabrasion produces very little downtime – a few hours of tingling and redness. But a deep chemical peel can keep you at home on painkillers for as much as 2 weeks. Dermabrasion and laser resurfacing will leave your skin red and swollen for around ten days, total recuperation can be up to three weeks. Because they are non-ablative, CO2 and Fraxel lasers, Thermage, and IPL treatments do not produce significant downtime, but the claim of ‘no downtime’ is somewhat exaggerated. For instance, some Thermage and CO2 patients develop redness and swelling that may last 2 to 3 days; residual pain may linger for several days. MTS Roller™ is non-ablative and produces little downtime – skin may be red and sensitive for about two to three hours after treatment. Skin Treatment Comparison MTS Roller with MTS Treatment: Less Invasive, Less Expensive, More Effective Risks And Side Effects There are ample horror stories about inadequate care by professionals when performing dermabrasion, chemical peels and laser resurfacing. Not only do these procedures require a great deal of training to master, they also require some amount of artistry in judging how much of the skin to remove; too little and the patient walks away with less than what they paid for, too much and there could be permanent damage like scarring or pigmentation changes. Moreover, these treatments may not be suitable for people with darker skin. Meanwhile, new machine-based treatments like CO2 lasers, Thermage, IPL, and other non-ablative do not exhibit many side effects, but the performance/artistry risks are the same. Microdermabrasion appears to have the advantage of exhibiting few side effects and little risk due to a large degree because it is a less invasive procedure. As such, however microdermabrasion has limited effectiveness on removing deeper acne scars, wrinkles, age spots or stretch marks. MTS Roller™ has none of the common risks and offers all of the advantages of the most invasive and most expensive treatments. The needles can only go into the skin so far – that’s why there are six different models. The only variable is for the practitioner to determine which of the rollers to use. Even if he goes too deep, the damage is minimal and not permanent. Moreover, clinical studies have shown that the mesotherapeutic effect of MTS 0.5mm roller outperforms all ablatives treatments (chemical peel, dermabrasion, laser resurfacing) and CO2 laser, Fraxel, and IPL in terms of delivering smoother skin and a long lasting effect.

BACKGROUND OF PERCUTANEOUS COLLAGEN INDUCTION THERAPY Facial skin resurfacing can be traced to ancient Egyptian times and the application of abrasive masks of alabaster particles. For millennia, various substances have been used to peel, exfoliate, and rejuvenate the skin. These substances include acids, poultices of minerals and plants, and direct irritants such as fire and sandpaperlike materials. The Early Stage The evolution of chemical peeling and skin abrasion into the procedures in common use today began in the early 20th century. In 1905, a German dermatologist Kromayer first reported controlled resurfacing abrasion of the skin. His technique involved the use of rotating wheels and rasps and, except for technical improvements of the equipment, differed very little from present-day skin abrasion. He treated acne scars, keratoses, and areas of hyperpigmentation. Despite this early report of the use of surgical planing, skin abrasion did not gain widespread popularity until the early 1950s, when Kurtin, McEvitt, and others published numerous articles on skin abrasion, leading to a rediscovery of the technique. Kurtin presented the first series of patients who underwent skin abrasion to Mount Sinai Hospital in 1953. Kurtin described the use of high-speed rotary abraders, intraoperative freezing, and a variety of abrasive end pieces. Moderate skin abrasion technique was developed in Italy in early 1980's by Swissfrench dermatologist, Dr. Philippe Simonin utilizing electroridopuncture technique with microcurrent and acupuncture needling; its use was widespread in European countries prior to its introduction and popularity in the United States. Subcision The first to notice the major advantages of skin needling were Orentreich et al in 1995. They were the first to introduce the term Subcision® from the contraction of the term ‘‘Subcutaneous Incinsionless’’ surgery. It is a method of cutting under a depressed scar, wrinkle or contour using a tri-beveled hypodermic needle inserted under the skin through a needle puncture, adjacent to the scar. The procedure attempts to raise the base of the defect to the level of the surrounding skin surface by 2 distinct mechanisms: The act of surgically releasing the skin from its attachment to deeper tissues results in skin elevation. The introduction of a controlled trauma initiates wound healing with consequent formation of connective tissue that augments the depressed scar. The technique involves 3 different approaches: simple linear inserting-withdrawing movement of the needle under the scar. fanning horizontal movement of the needle under the scar. vertical movement of the needle under the scar. Advanced Needle Abrasion The next important publication concerning skin needling was reported by Dr. Andre Camirand et al. who in his article in 1997 described his experience with this method. On a number of his patients with facial hypochromic scars, he tattooed the scars with a skin-color pigment. After 1-2 years, they noticed that even though the pigment was long gone, it was replaced by actual melanin, while the scars were immensely improved in texture, appearance and color. This gave the idea that trepenation (coming from the Greek word –Trepanon: to bore) of scars with the tattoo gun was responsible for the improvement and the repigmentation of the scar. They came up with the idea that puncturing of the scar with a tattoo gun alone, without pigment, would in a way break down the scar collagen, cause realignment and stimulate melanogenesis. The results of repetitive sessions on scars were reported by Camirand et al. to be more than good and typically consistent, since all of his patients profited aesthetically from this type of treatment.   Needle Stamp designed by Dr. Des Fernandes   Following to Dr Camirand's development, Dr. Des Fernandes introduced needling device, a small needle stamp, to induce collagen and used as a regular treatment in his surgical practice. He delivered his first paper on skin needling of the upper lips to the ISAPS congress in Taipei 1996. Development of Advanced Needle Device After extensive research and further development of the skin needle abrasion technology, Clinical Resolution Laboratory, a California Company in U.S.A., re-invented new pattern of the device, called MTS Roller, and released the instrument to the public in 2004. The First generation of MTS Roller by Clinical Resolution Laboratory        . Comparing the all abovementioned techniques with the MTS Roller, it is evident that the MTS Roller combines the best features of both techniques and at the same time offers additional advantages. Rolling of the MTS Roller over the skin will cause hundreds of miniscule wounds on the dermis, while creating tiny holes on the epidermis, which will close in hours. This will start up an aseptic inflammation process, which will result in collagen production. The number of punctures caused by the MTS Roller‚ is dozens of times more than the number of punctures created by a tattoo gun or any other methodes developed prior. The Birth of Microneedle Therapy System After the great invention of MTS Roller, there was still a missing link between MTS Rollers and its application & use to benefit people in an easy, convenient manner. In the endless efforts to apply the concept of the dermaroller in our daily life against their aging process and to make a difference in our lives, Clinical Resolution Lab (CRL) has completed a missing link with its clinically proven peptide based products in the below treatment areas. In 2004, CRL launched “Mirconeedle Therapy System Association” to further develop the extended needs and undiscovered application of the MTS Rollers, which will function as a centralized MTS education center as well as systematically well-organized worldwide MTS forum. We have defined the entire cosmeceutical treatments using MTS Rollers as Microneedle Therapy System (MTS) in the world. The core MTS treatments include; Natural Collagen Inducing Therapy against acute and/or chronic aging. Enhanced Wound Healing Solution via Transdermal Drug Delivery System Obesity (Fatty Cell) Stretch Mark Acne Scar Removal Psoriasis, Itchiness & Atopy Nucleic Acids (DNA/RNA & their protein synthesis Solution) Alopecia – Hair Restoration Pigment Stabilization Growth Hormone Stimulating Peptides/Amino Acids Anesthetic Crème   THE BEST OF NEEDLE REFINING TECHNOLOGY Advances in the processing of materials on a micro-scale have led to the development and introduction of devices that employ very small needles – microneedles – that deliver drugs by mechanically perforating the out skin layer and allowing for transdermal absorption of the active compound. These processing techniques incorporate one or more technologies that enable the precise machining, extrusion, casting, and/or forming of from one to an array or grid of microneedles. Microneedles are generally arranged in so-called microfibricated arrays. They are synthesized by reactive ion etching techniques on silicon or other types of material, in order to create microscopic arrays of needles, measuring 100-1000µm in length and 10-15µm in tip diameter. When these needles are inserted into skin, they pierce the stratum corneum and create microconduits for transport across the stratum corneum. Microneedles may be small enough to capture the convenience of patches but large enough to create micrometer-scale pathways across the skin for drug delivery of even the largest macromolecules. Microneedles can be painlessly inserted into the skin of human subjects and their use does not need any medical expertise. The MTS Roller™ series shares all of the advantages of the typical microneedle array, but have also a unique way of mechanically driving the applied substance under the skin, through the holes already created by the MTS Roller™ needles. The needles on the surface of the MTS Roller™ create miniscule holes of 0.07mm diameter and 0.13mm to 2.5mm in depth, while the cylinder itself literally pushes mechanically the applied substance inside the holes and finally under the skin. The MTS Roller, a barrel-like roller with 200 incorporated micro-points, is made by the world's best German grinding skill with patented needle-tip hardening technology to provide the safest medical skin treatment. They are so fine and short that an injury of the dermis is impossible when handled according to the instruction. All components used are friendly to the skin with no known negative side-effects than any other skin treatment methodes.